Solvent Based Extraction and Phytochemical and Biological activities of Teucrium Stocksianum

Abstract

Throughout human civilization, plants have been a provider of inspiration for innovative medication, as plant-based medicines have significantly improved human health and wellbeing. Around 10,000 to 53,000 plant species are utilized as traditional medicines around the world, but very few of these treatments have undergone biological screening, which is a necessary step before validating and examining the full pharmacological potential of these plants. Teucrium stocksianum is one of the economically significant medicinal plants. To determine the most effectual plant sample and solvent system for bioactivity, a range of solvent extracts (distilled water, methanol, ethanol, acetone, ethyl acetate, n-hexane, chloroform) were put through phytochemical and biological tests. The methanolic extract of leaves had the highest. TPC, TFC, DPPH, TAC, and TRP values of all the extracts (38.92 ± 1.94 µg/GAE/mg, 40.39 ± 2.01 µg/QE/mg, 87.29 ± 4.36%, 298.59 ± 14.92 µg/ AAE/mg, and 218.20 ± 10.91 µg/ AAE/mg, respectively). Whereas methanolic extract of stem and root displayed the highest ABTS value (91. 92 ± 4.59%, and 91.31 ± 4.56 % respectively). The highest values of MC %, alpha-amylase, urease, and lipase inhibitory activities were unveiled by the aqueous extract of leaves (64.42 ± 3.32%, 88.57 ± 4.42%, 78.71 ± 3.93%, and 72.89 ± 3.64% respectively). Methanolic extract of root displayed anti-microbial potential against six gram-positive and gram-negative bacterial strains. The results showed that T. stocksianum can be thought of as an alternative source of antioxidants, anticancer, and antimicrobial chemicals. Additionally, it underlines the necessity of further screening, isolation, and characterization of its biologically active components and supports the traditional therapeutic usage of T. Stocksianum