Prevalence of PCOS and its Association with Psychological Disorders among Women of Reproductive Age Visiting Rehab Facilities of Islamabad

Abstract

Back ground: PCOS is often characterized by hyper-androgenism. In hyper-androgenism, a female produces the higher levels of androstenedione. PCOS is also associated with rise of psychological disorder and screening for the disorders necessary to allow for early interventions. Objectives: The main aim of this study is to find the prevalence of PCOS in women and its association with psychological disorder visiting rehab facilities of Islamabad. Methodology: the study was conducted in two rehab facilities of Islamabad, which were chosen by multi cluster random sampling. Data was collected from the female in their reproductive age with and without PCOs meeting the inclusion criteria using interview based and online questionnaires, psychological disorder were assessed using DASS-21 scale. Data were analyzed in SPSS version 25. Results: A total of 384 women of reproductive age visiting rehab facilities participated in this study in which 34.82% (n=135) women diagnosed with PCOS, while the percentage of normal women with no PCOS was 65.11% (n=250). A significant association was found between prevalence of PCOs and regular health checkup. (x² (1) = 8.403, p-value = 0.004), as evidenced by the chi-square test of association. Prevalence of PCOs and body weight were significantly associated (x² (1) = 6.553, p-value = 0.010). While physical activity, consider nutrients, and eat junk food was also significantly associated with PCOS (x² (2) = 79.010, p-value = 0.011), (x² (1) = 8.720, p-value = 0.003) and (x² (1) = 8.149, p-value = 0.004) respectively. Conclusion: The overall prevalence of PCOs is high among women of reproductive age which is increasing the overall health, social and economic burden. Percentage of depression, anxiety and stress with PCOs was low as compared to without PCOS. Lifestyle and dietary modifications play a significant role in development of PCOs. our study also found that the percentage of depression, anxiety, and stress with PCOS was low as compared to without PCOS. Keywords: Polycystic ovarian syndrome, depression, anxiety and stress scale