NUCLEOPHILIC SUBSTITUTION IN AROMATIC SYSTEMS

Abstract

Understanding of basic concepts, with logical conclusions is an important factor for learning and teaching of organic chemistry. With this view recent developments in the field of nucleophilic substitutions in aromatic systems are considered in the light of experimental results available in chemical literature. The monogragh deals with nucleophilic displacements on benzene and its polycyclic systems, nonbenzenoid aromatics and heterocyclic systems including arynes and Meisenheimer complexes. Generalised form of reaction schemes are illustrated and discussed with the view to help reader in understanding the subject with a systematic approach. Breakdown pattern of the reaction intermediates are particularly emphasized. Various polarising factors demanding structures and reactivity relationship are included alongwith some rearrangement reactions pertaining to this class of reactions . I would like to acknowledge my thanks for the understanding I have received from my wife during the preparation of this monograph and in particular to Dr. Rashid Iqbal for reading whole of the manuscript and stimulating discussions. I feel indebted to Dr. Afzal Ahmad for reading a portion of this volume and his critical suggestions. I should like to express my gratitude to Dr. M.Afzal, Chairman Department of Chemistry for encouragement during the preparation of this monograph. I am also. obliged to my students who over the past years helped in collecting the research information and to Mr. M. Akbar for drawings and sketches.